|
|
phosphatidic_acid + H2O <=> diacylglycerol + phosphate
|
3.1.3.4
phosphatidate phosphatase
3.1.3.81
diacylglycerol diphosphate phosphatase
3.1.4.3
phospholipase C
|
–
–
–
|
MK
|
|
BRENDA:
BR15942;
BS446013
KEGG:
R02239
MetaCyc:
PHOSPHATIDATE-PHOSPHATASE-RXN
|
|
|
|
phosphatidylcholine + H2O <=> phosphatidic_acid + choline + H+
|
3.1.4.4
phospholipase D
3.1.4.41
sphingomyelin phosphodiesterase D
|
–
–
|
BMK
|
|
BRENDA:
BR15961
KEGG:
R01310
MetaCyc:
PHOSCHOL-RXN
SABIO-RK:
1525
|
|
|
|
CDP-diacylglycerol + H2O <=> phosphatidic_acid + CMP + H+
|
2.7.8.8
CDP-diacylglycerol---serine O-phosphatidyltransferase
3.6.1.26
CDP-diacylglycerol diphosphatase
|
–
–
|
K
|
|
BRENDA:
BR22767
KEGG:
R01797
MetaCyc:
CDPDIGLYPYPHOSPHA-RXN
|
|
|
|
acyl-CoA + lysophosphatidic_acid <=> phosphatidic_acid + CoA
|
2.3.1.51
1-acylglycerol-3-phosphate O-acyltransferase
|
–
|
BMK
|
|
BRENDA:
BR44053
KEGG:
R02241
MetaCyc:
RXN-1623
|
|
|
|
acyl-CoA + 2-acyl-sn-glycerol_3-phosphate <=> phosphatidic_acid + CoA
|
2.3.1.52
2-acylglycerol-3-phosphate O-acyltransferase
|
–
|
K
|
|
BRENDA:
BR44054
KEGG:
R02242
MetaCyc:
2-ACYL2.3.1.15-RXN
|
|
|
|
ATP + diacylglycerol <=> H+ + phosphatidic_acid + ADP
|
2.7.1.107
diacylglycerol kinase (ATP)
2.7.1.138
ceramide kinase
2.7.1.94
acylglycerol kinase
|
–
–
–
|
MK
|
|
BRENDA:
BR47721
KEGG:
R02240
MetaCyc:
DIACYLGLYKIN-RXN
SABIO-RK:
2211
|
|
|
|
CTP + phosphatidic_acid + H+ <=> CDP-diacylglycerol + diphosphate
|
2.7.7.41
phosphatidate cytidylyltransferase
|
–
|
BMK
|
|
BRENDA:
BR47885
KEGG:
R01799
MetaCyc:
CDPDIGLYSYN-RXN
SABIO-RK:
336
|
|
|
|
6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H2O <=> phosphatidic_acid + 1-O-(2-amino-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol + H+
|
3.1.4.50
glycosylphosphatidylinositol phospholipase D
|
–
|
|
|
BRENDA:
BR48170
KEGG:
R07398
MetaCyc:
GLYCOPROTEIN-PHOSPHOLIPASE-D-RXN
|
|
|
|
diacylglycerol_diphosphate + H2O <=> phosphatidic_acid + phosphate + H+
|
3.1.3.4
phosphatidate phosphatase
3.1.3.81
diacylglycerol diphosphate phosphatase
3.6.1.27
undecaprenyl-diphosphate phosphatase
|
–
–
–
|
M
|
|
BRENDA:
BR48896
KEGG:
R09644
MetaCyc:
RXN-11277
|
|
|
|
CTP + diacylglycerol <=> CDP + phosphatidic_acid + H+
|
2.7.1.174
diacylglycerol kinase (CTP)
|
–
|
MK
|
|
BRENDA:
BR49008
KEGG:
R09944
MetaCyc:
RXN-12959
|
|
|
|
N-acylphosphatidylethanolamine + H2O <=> N-acylethanolamine + phosphatidic_acid + H+
|
3.1.4.4
phospholipase D
3.1.4.54
N-acetylphosphatidylethanolamine-hydrolysing phospholipase D
|
–
–
|
|
|
BRENDA:
BR49488
MetaCyc:
RXN-12116
|
|
|
|
acyl-[acyl-carrier_protein] + lysophosphatidic_acid <=> phosphatidic_acid + [acyl-carrier_protein]
|
2.3.1.51
1-acylglycerol-3-phosphate O-acyltransferase
|
–
|
M
|
|
BRENDA:
BS321039
KEGG:
R09381
MetaCyc:
1-ACYLGLYCEROL-3-P-ACYLTRANSFER-RXN
|
|
|
|
N-palmitoyl-phosphatidylethanolamine + H2O <=> N-palmitoylethanolamine + phosphatidic_acid + H+
|
3.1.4.4
phospholipase D
3.1.4.54
N-acetylphosphatidylethanolamine-hydrolysing phospholipase D
|
–
–
|
M
|
|
BRENDA:
BS364663
MetaCyc:
RXN-20516
|
|
|
|
N-arachidonoylphosphatidylethanolamine + H2O <=> anandamide + phosphatidic_acid + H+
|
3.1.4.4
phospholipase D
3.1.4.54
N-acetylphosphatidylethanolamine-hydrolysing phospholipase D
|
–
–
|
M
|
|
BRENDA:
BS364664
MetaCyc:
RXN-20502
|
|
|
|
N-oleoylphosphatidylethanolamine + H2O <=> N-oleoylethanolamine + phosphatidic_acid + H+
|
3.1.4.54
N-acetylphosphatidylethanolamine-hydrolysing phospholipase D
|
–
|
|
|
BRENDA:
BS412546
MetaCyc:
RXN-20517
|
|
|
|
N-stearoylphosphatidylethanolamine + H2O <=> N-stearoylethanolamine + phosphatidic_acid + H+
|
3.1.4.54
N-acetylphosphatidylethanolamine-hydrolysing phospholipase D
|
–
|
|
|
BRENDA:
BS412560
MetaCyc:
RXN-20515
|
|
|
|
phosphatidylethanolamine + H2O <=> ethanolamine + phosphatidic_acid
|
3.1.4.4
phospholipase D
|
–
|
K
|
|
BRENDA:
BS364671
KEGG:
R02051
|
|
|
|
dCTP + phosphatidic_acid <=> diphosphate + dCDP-diacylglycerol
|
2.7.7.41
phosphatidate cytidylyltransferase
|
–
|
|
|
BRENDA:
BS358565
SABIO-RK:
13693
|
|
|
|
trans-2-enoyl-CoA + lysophosphatidic_acid <=> CoA + phosphatidic_acid
|
2.3.1.51
1-acylglycerol-3-phosphate O-acyltransferase
|
–
|
|
|
KEGG:
R02760
|
|
|
|
Glycoprotein_phosphatidylinositol + H2O <=> phosphatidic_acid + glycoprotein_inositol
|
3.1.4.50
glycosylphosphatidylinositol phospholipase D
|
–
|
|
|
KEGG:
R04149
|
|
|
|
alpha-D-GlcN-(1->6)-Ino-P + H2O <=> Glucosaminyl-alpha-1,6-D-myo-inositol + phosphatidic_acid
|
3.1.4.50
glycosylphosphatidylinositol phospholipase D
|
–
|
K
|
|
KEGG:
R06623
|
|
|
|
phosphatidic_acid + ATP <=> diacylglycerol_diphosphate + ADP
|
2.7.4
|
–
|
M
|
|
MetaCyc:
RXN-13336
|
|
|
|
acyl-[acyl-carrier_protein] + 2-acyl-sn-glycerol_3-phosphate <=> phosphatidic_acid + [acyl-carrier_protein]
|
2.3.1
|
–
|
|
|
MetaCyc:
RXN-16075
|
|
|
|
N-linoleoyl-phosphatidylethanolamine + H2O <=> N-(2-hydroxyethyl)linoleoylamide + phosphatidic_acid + H+
|
3.1.4.54
N-acetylphosphatidylethanolamine-hydrolysing phospholipase D
|
–
|
|
|
MetaCyc:
RXN-20518
|
|
|
|
phosphatidic_acid + H2O <=> 2-acyl-sn-glycerol_3-phosphate + fatty_acid + H+
|
3.1.1.ae
|
–
|
|
|
MetaCyc:
RXN-20541
|
|
|
|
dipalmitoylphosphatidylcholine + H2O <=> choline + phosphatidic_acid
|
3.1.4.4
phospholipase D
|
–
|
|
|
BRENDA:
BS400877
|
|
|
|
oleoyl-CoA + lysophosphatidic_acid <=> CoA + phosphatidic_acid
|
2.3.1.51
1-acylglycerol-3-phosphate O-acyltransferase
|
–
|
|
|
BRENDA:
BS389450
|
|
|
|
phosphatidylinositol + H2O <=> myo-inositol + phosphatidic_acid
|
3.1.4.3
phospholipase C
3.1.4.4
phospholipase D
|
–
–
|
|
|
BRENDA:
BS364653
|
|
|
|
diacylglycerol_diphosphate + alpha-D-Kdo-(2->4)-alpha-D-Kdo-(2->6)-lipid_A <=> phosphatidic_acid + alpha-D-Kdo-(2->4)-alpha-D-Kdo-(2->6)-lipid_A_1-diphosphate
|
2.7.4.29
Kdo2-lipid A phosphotransferase
|
–
|
|
|
BRENDA:
BS431811
|
|
|
|
doxorubicin + phosphatidic_acid <=> phosphatidyl-doxorubicin + H2O
|
3.1.4.4
phospholipase D
|
–
|
|
|
BRENDA:
BS447483
|
|
|
|
dCTP + diacylglycerol <=> dCDP + phosphatidic_acid
|
2.7.1.174
diacylglycerol kinase (CTP)
|
–
|
|
|
BRENDA:
BS418577
|
|
|
|
phosphatidic_acid + H2O <=> 1,2-dioleoyl-sn-glycerol + phosphate
|
3.1.3.4
phosphatidate phosphatase
|
–
|
|
|
BRENDA:
BS390282
|
|
|
|
phosphatidic_acid + H2O <=> dialkylglycerol + phosphate
|
3.1.3.59
alkylacetylglycerophosphatase
|
–
|
|
|
BRENDA:
BS360921
|
|
|
|
GTP + diacylglycerol <=> GDP + phosphatidic_acid
|
2.7.1.107
diacylglycerol kinase (ATP)
|
–
|
|
|
BRENDA:
BS452234
|
|
|
|
Phospholipid + H2O <=> phosphatidic_acid + an_alcohol
|
3.1.4.4
phospholipase D
|
–
|
|
|
BRENDA:
BS369743
|
|
|
|
phosphatidylglycerol + H2O <=> glycerol + phosphatidic_acid
|
3.1.4.4
phospholipase D
|
–
|
|
|
BRENDA:
BS382559
|
|
|
|
phosphatidylglycerol + H2O <=> L-alpha-glycerophosphate + phosphatidic_acid
|
3.1.4.4
phospholipase D
|
–
|
|
|
BRENDA:
BS93709
|
|
|
|
phosphatidylglycerol + H2O <=> diacylglycerol + phosphatidic_acid
|
3.1.4.3
phospholipase C
|
–
|
|
|
BRENDA:
BS430602
|
|
|
|
Membrane_form_of_variant-surface-glycoprotein + H2O <=> phosphatidic_acid + variant-surface-glycoprotein_inositol
|
3.1.4.50
glycosylphosphatidylinositol phospholipase D
|
–
|
|
|
BRENDA:
BS360983
|
|
|
|
Phosphatidylinositol-glycan-anchored_membrane_form_of_acetylcholinesterase + H2O <=> Soluble_acetylcholinesterase + phosphatidic_acid
|
3.1.4.50
glycosylphosphatidylinositol phospholipase D
|
–
|
|
|
BRENDA:
BS360984
|
|
|
|
glycosylphosphatidylinositol-anchored_proteins <=> phosphatidic_acid + variant_membrane_protein
|
3.1.4.50
glycosylphosphatidylinositol phospholipase D
|
–
|
|
|
BRENDA:
BS392150
|
|
|
|
glycosylphosphatidylinositol-membrane_anchor_of_Cripto-1 <=> soluble_Cripto-1 + phosphatidic_acid
|
3.1.4.50
glycosylphosphatidylinositol phospholipase D
|
–
|
|
|
BRENDA:
BS392151
|
|
|
|
cardiolipin + H2O <=> L-alpha-glycerophosphate + phosphatidic_acid
|
3.1.4.4
phospholipase D
|
–
|
|
|
BRENDA:
BS93708
|
|
|
|
phosphatidic_acid + H2O <=> lysophosphatidic_acid + fatty_acid
|
3.1.1.111
phosphatidylserine sn-1 acylhydrolase
3.1.1.4
phospholipase A2
|
–
–
|
|
|
BRENDA:
BS450466
|
|
|
|
phosphatidic_acid + H2O <=> 2-acyl-sn-glycerol_3-phosphate + a_carboxylate
|
3.1.1.32
phospholipase A1
|
–
|
|
|
BRENDA:
BS364098
|
|
|
|
phosphatidic_acid + H2O <=> lysophosphatidic_acid + a_carboxylate
|
3.1.1.32
phospholipase A1
|
–
|
|
|
BRENDA:
BS364107
|
|
|
|
phosphatidyl-p-nitrophenol + H2O <=> phosphatidic_acid + 4-nitrophenol
|
3.1.4.4
phospholipase D
|
–
|
|
|
BRENDA:
BS382557
|
|
|
|
ATP + 1,2-dioleoyl-sn-glycerol <=> ADP + phosphatidic_acid
|
2.7.1.107
diacylglycerol kinase (ATP)
|
–
|
|
|
BRENDA:
BS400012
|
|
|
|
N-lauroyl-phosphatidylethanolamine + H2O <=> phosphatidic_acid + lauroylethanolamide
|
3.1.4.4
phospholipase D
|
–
|
|
|
BRENDA:
BS392799
|
|
|
|
phosphatidylserine + H2O <=> L-serine + phosphatidic_acid
|
3.1.4.4
phospholipase D
|
–
|
|
|
BRENDA:
BS364672
|
|
|
|
phosphatidylinositol_4,5-bisphosphate + H2O <=> 1D-myo-inositol_4,5-bisphosphate + phosphatidic_acid
|
3.1.4.3
phospholipase C
|
–
|
|
|
BRENDA:
BS364654
|
|